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Breast Cancer Update: A CME Audio Series and Activity

Statement of Need /Target Audience

Breast cancer is one of the most rapidly evolving fields in medical oncology. Published results from a plethora of ongoing clinical trials lead to the continuous emergence of new therapeutic agents and changes in the indications for existing treatments. In order to offer optimal patient care — including the option of clinical trial participation — the practicing medical oncologist must be well informed of these advances. To bridge the gap between research and patient care, Breast Cancer Update utilizes one-on-one discussions with leading oncology investigators. By providing access to the latest research developments and expert perspectives, this CME program assists medical oncologists in the formulation of up-to-date clinical management strategies.

Global Learning Objectives

Upon completion of this activity, participants should be able to:

  • Critically evaluate the clinical implications of emerging clinical trial data in breast cancer treatment.
  • Describe and implement an algorithm for HER2 testing and treatment of patients with HER2-positive breast cancer.
  • Develop a management strategy for women with ER-positive and -negative breast cancers in the adjuvant, neoadjuvant and metastatic settings.
  • Counsel postmenopausal patients with ER-positive tumors about the risks and benefits of aromatase inhibitors in the adjuvant setting.
  • Evaluate the relevance of emerging clinical trial data on dose-dense adjuvant chemotherapy.

Issue 1, 2003 of Breast Cancer Update consists of discussions with three research leaders on a variety of important topics including aromatase inhibitors in the adjuvant setting, dose-dense chemotherapy, ovarian ablation and the use of capecitabine.

Specific learning objectives for Issue 1

Upon completion of this activity, participants should be able to:

  • Describe the rationale for and results of clinical research on dose-dense adjuvant chemotherapy.
  • Counsel and make recommendations for individual ER-positive, postmenopausal patients regarding the use of adjuvant aromatase inhibitors.
  • Discuss the ongoing/planned clinical trials of capecitabine in the adjuvant and neoadjuvant settings.
  • Describe the clinical implications of research on combinations of chemotherapy with trastuzumab in women with HER2-positive metastatic disease.

Accreditation Statement

This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the Postgraduate Institute for Medicine and NL Communications, Inc. The Postgraduate Institute for Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statement

The Postgraduate Institute for Medicine designates this educational activity for a maximum of 3 category 1 credits toward the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.

Faculty Disclosure Statements

The Postgraduate Institute for Medicine has a conflict of interest policy that requires course faculty to disclose any real or apparent commercial financial affiliations related to the content of their presentations/materials. It is not assumed that these financial interests or affiliations will have an adverse impact on faculty presentations; they are simply noted in this supplement to fully inform participants.

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Larry Norton, MD
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Gabriel N Hortobagyi, MD
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Nancy E Davidson, MD
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