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Use of aromatase inhibitors in the adjuvant setting

Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial. Lancet 2002;359(9324):2131-9. Abstract

Pharmacokinetics of anastrozole and tamoxifen alone, and in combination, during adjuvant endocrine therapy for early breast cancer in postmenopausal women: A sub-protocol of the 'Arimidex and Tamoxifen Alone or in Combination' (ATAC) trial. Br J Cancer 2001;85(3):317-24. Abstract

Baum M. The ATAC (Arimidex, Tamoxifen, Alone or in Combination) adjuvant breast cancer trial in postmenopausal patients: Factors influencing the success of patient recruitment. Eur J Cancer 2002;38(15):1984. Abstract

Baum M. A vision for the future? Br J Cancer 2001;85 Suppl 2:15-8. Abstract

Bianco AR. ATAC (‘Arimidex’, Tamoxifen, Alone or in Combination) trial — Anastrozole is superior to tamoxifen as adjuvant treatment in postmenopausal women with early breast cancer. Breast Cancer Res Treat 2002; Abstract 632.

Buzdar A. The ATAC ('Arimidex', Tamoxifen, Alone or in Combination) trial in postmenopausal women with early breast cancer — Updated efficacy results based on a median follow-up of 47 months. Breast Cancer Res Treat 2002; Abstract 13.

Buzdar AU. New generation aromatase inhibitors — From the advanced to the adjuvant setting. Breast Cancer Res Treat 2002;75 Suppl 1:S13-7; discussion S33-5. Abstract

Buzdar AU. Anastrozole (Arimidex) — An aromatase inhibitor for the adjuvant setting? Br J Cancer 2001;85 Suppl 2:6-10. Abstract

Goss PE. Preliminary data from ongoing adjuvant aromatase inhibitor trials. Clin Cancer Res 2001;7(12 Suppl):4397s-4401s; discussion 4411s-4412s. Abstract

Jones SE. Antiaromatase agents: Evolving role in adjuvant therapy. Clin Breast Cancer 2002;3(1):33-42. Abstract

Mokbel K. The evolving role of aromatase inhibitors in breast cancer. Int J Clin Oncol 2002;7(5):279-83. Abstract

Ragaz J. Adjuvant trials of aromatase inhibitors: Determining the future landscape of adjuvant endocrine therapy. J Steroid Biochem Mol Biol 2001;79(1-5):133-41. Abstract

Sainsbury R. Beneficial side-effect profile of anastrozole compared with tamoxifen confirmed by additional 7 months of exposure data: A safety update from the ’Arimidex’, Tamoxifen, Alone or in Combination (ATAC) trial. Breast Cancer Res Treat 2002; Abstract 633.

Wellington K, Faulds DM. Anastrozole in early breast cancer. Drugs 2002;62(17):2485-92. Abstract

Winer EP et al. American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for women with hormone receptor-positive breast cancer: Status report 2002. J Clin Oncol 2002;20(15):3317-27. Abstract

Adjuvant chemotherapy for patients with node-negative breast cancer Aapro MS. Adjuvant therapy of primary breast cancer: A review of key findings from the 7th International Conference, St. Gallen, February 2001. Oncologist 2001;6(4):376-85. Abstract

Abrams JS. Adjuvant therapy for breast cancer — Results from the USA consensus conference. Breast Cancer 2001;8(4):298-304. Abstract

Boyages J et al. Use of the St Gallen classification for patients with node-negative breast cancer may lead to overuse of adjuvant chemotherapy. Br J Surg 2002;89(6):789-96. Abstract

Buchholz TA et al. Impact of systemic treatment on local control for patients with lymph nodenegative breast cancer treated with breast-conservation therapy. J Clin Oncol 2001;19(8):2240-6. Abstract

Fisher B et al. Prognosis and treatment of patients with breast tumors of one centimeter or less and negative axillary lymph nodes. J Natl Cancer Inst 2001;93(2):112-20. Abstract

Fisher B et al. Findings from recent National Surgical Adjuvant Breast and Bowel Project adjuvant studies in stage I breast cancer. J Natl Cancer Inst Monogr 2001;(30):62-6. Abstract

Fisher B et al. Tamoxifen and chemotherapy for axillary node-negative, estrogen receptor-negative breast cancer: Findings from National Surgical Adjuvant Breast and Bowel Project B-23. J Clin Oncol 2001;19(4):931-42. Abstract

Joly F et al. Long-term quality of life in premenopausal women with node-negative localized breast cancer treated with or without adjuvant chemotherapy. Br J Cancer 2000;83(5):577-82. Abstract

Jones SE et al. Adjuvant chemotherapy with doxorubicin and cyclophosphamide in women with rapidly proliferating node-negative breast cancer. Clin Breast Cancer 2002;3(2):147-52. Abstract

Morrow M, Krontiras H. Who should not receive chemotherapy? Data from American databases and trials. J Natl Cancer Inst Monogr 2001;(30):109-13. Abstract

 

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Larry Norton, MD
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Gabriel N Hortobagyi, MD
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Nancy E Davidson, MD
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