You are here: Home: Audio Program Guide: BCU 4 | 2007 Audio: BCU 4 | 2007
 
  Go to interview with Edith A Perez, MD
Go to interview with Sandra M Swain, MD
Go to interview with Kathleen I Pritchard, MD
Go to interview with Martine J Piccart-Gebhart, MD, PhD
Go to interview with Ruth O’Regan, MD

 

 

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Perez, MD Edith A Perez, MD
Professor of Medicine, Mayo Medical School
Director, Cancer Clinical Study Unit
Director, Breast Cancer Program, Division of
Hematology and Oncology, Mayo Clinic
Jacksonville, Florida



 
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Track 1 Predictors of response to adjuvant endocrine therapy
Track 2 TAnDEM study: Anastrozole with or without trastuzumab as first-line therapy of metastatic disease
Track 3 NCCTG-N0337: Nonalopecic regimen of capecitabine, vinorelbine and trastuzumab as first- or second-line therapy
Track 4 Use of adjuvant trastuzumab monotherapy for elderly patients
Track 5 Perspective on the second interim analysis of BCIRG 006
Track 6 Efficacy and safety results from the second interim analysis of BCIRG 006

Track 7 Incorporation of ACE inhibitors with AC arrow taxane/trastuzumab to ameliorate cardiotoxicity
Track 8 Role of TCH in treating HER2-positive, early breast cancer
Track 9 Treatment for smaller, HER2-positive, node-negative tumors
Track 10 Clinical trials combining bevacizumab with chemotherapy/trastuzumab for HER2-positive disease
Track 11 Background of BIG 2-06: Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization study (ALTTO)
Track 12 Eligibility for ALTTO
Track 13 Treatment randomization on ALTTO
Track 14 Safety and efficacy data with trastuzumab and lapatinib in combination
Track 15 Lapatinib cardiac safety data
Track 16 First-line therapy after progression on a trastuzumab-containing regimen
Track 17 Continuing clinical development of nanoparticle albumin-bound (nab) paclitaxel
Track 18 Weekly or every three-week nab paclitaxel versus docetaxel as first-line therapy
     
Swain, MD Sandra M Swain, MD
Medical Director, Washington Cancer Institute
Washington Hospital Center
Washington, DC


 
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Track 1 Long-term cardiotoxicity from anthracycline-containing adjuvant chemotherapy
Track 2 Use of adjuvant docetaxel/cyclophosphamide (TC) for patients with HER2-negative disease
Track 3 Tolerability of adjuvant TC
Track 4 NSABP-B-38: Adjuvant TAC versus dose-dense AC arrow paclitaxel with or without gemcitabine for node-positive breast cancer
Track 5 Clinical implications of chemotherapy-induced amenorrhea
Track 6 NSABP-B-40: Neoadjuvant trial of capecitabine or gemcitabine with docetaxel administered before AC with or without bevacizumab

Track 7 Anti-angiogenic and antitumor effects of bevacizumab in inflammatory and locally advanced breast cancer
Track 8 Effect of bevacizumab on tumor blood flow
Track 9 Bevacizumab and wound healing
Track 10 Proposed NSABP/BCIRG trial evaluating TCH with or without bevacizumab for HER2-positive, early
breast cancer
Track 11 Use of adjuvant TCH for patients with HER2- positive disease
Track 12 Adjuvant trastuzumab for patients with small, node-negative tumors
Track 13 Oncotype DX™ recurrence score and benefit of chemotherapy in node-negative, hormone receptor-positive breast cancer
audio
Track 14 TAILORx study; Microarray in Node-negative Disease may Avoid ChemoTherapy (MINDACT) study evaluating the clinical utility of gene expression profiles
audio
Track 15 Use of Oncotype DX and RT-PCR to assess hormone receptor and HER2 status
audio
Track 16 Clinical implications of the natural history of hormone receptor-positive breast cancer
audio
     
Pritchard, MD Kathleen I Pritchard, MD
Head, Clinical Trials and Epidemiology
Toronto Sunnybrook Regional Cancer Centre
Professor, Department of Medicine
Faculty of Medicine, University of Toronto
Toronto, Canada


 
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Track 1 Adjuvant aromatase inhibitors for postmenopausal patients with hormone receptor-positive disease
Track 2 Duration of adjuvant therapy with an aromatase inhibitor
Track 3 ATLAS and aTTom: Five versus 10 years of adjuvant tamoxifen
Track 4 Arthralgias associated with the aromatase inhibitors
Track 5 Adjuvant aromatase inhibitors and cardiovascular disease
Track 6 Delayed adjuvant treatment with aromatase inhibitors

Track 7 Management of aromatase inhibitor-associated bone loss
Track 8 Adjuvant hormonal therapy for premenopausal patients with hormone receptor-positive disease
Track 9 EFECT: Fulvestrant versus exemestane following nonsteroidal aromatase inhibitor therapy
Track 10 Sequencing hormonal therapy in the metastatic setting
Track 11 Neoadjuvant hormonal therapy
audio
Track 12 Advances in adjuvant chemotherapy
audio
Track 13 Evaluation of bevacizumab in the adjuvant setting
audio
Track 14 Adjuvant chemotherapy for patients with node-positive and node-negative breast cancer
audio
Track 15 Adjuvant chemotherapy for patients with hormone receptor-positive disease
audio
Track 16 TAILORx: Hormonal therapy with or without chemotherapy for patients with node-negative disease and various levels of recurrence risk
audio
Track 17 Controversies in the treatment of HER2-positive, early breast cancer
audio
Track 18 Treatment of HER2-positive, metastatic disease
audio
Track 19 TAnDEM: Anastrozole with or without trastuzumab for HER2-positive, metastatic disease
audio
Track 20 Evolution of clinical trial data with bevacizumab in breast cancer
audio
Track 21 Potential mechanisms of action of bevacizumab
audio
Track 22 ALTTO and proposed NSABP/BCIRG adjuvant HER2-positive trials

     
Piccart-Gebhart, MD Martine J Piccart-Gebhart, MD, PhD
Head, Medicine Department
Breast International Group
Chair, Medical Oncology Clinic
Jules Bordet Institute
Brussels, Belgium

 
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Track 1 Development of the 70-gene MammaPrint® assay
Track 2 BIG 3-04: The MINDACT trial
Track 3 Use of MammaPrint or Oncotype DX in clinical practice
Track 4 Second interim analysis of the BCIRG 006 trial of adjuvant trastuzumab
Track 5 Selection of an adjuvant chemotherapy regimen to combine with trastuzumab for HER2-positive, early breast cancer
Track 6 ALTTO: Adjuvant trastuzumab, lapatinib, the combination or the sequence

Track 7 Chemotherapy regimens allowed in ALTTO
Track 8 Eligibility criteria for ALTTO
Track 9 Treatment of smaller, node-negative, HER2-positive tumors
Track 10 Proposed NSABP/BCIRG adjuvant HER2 trial of TCH with or without bevacizumab
Track 11 Duration of adjuvant trastuzumab
audio
Track 12 Selection of adjuvant chemotherapy for patients with triple-negative disease
audio
Track 13 CAN-NCIC-MA21: Adjuvant CEF, dose-dense EC arrow paclitaxel (P) or AC arrowP
audio
Track 14 Differential effects of adjuvant chemotherapy in luminal A and B hormone receptor-positive breast cancer
audio
Track 15 Adjuvant treatment of postmenopausal patients with hormone receptor-positive disease
audio
Track 16 SOFT and TEXT: Optimizing adjuvant hormonal therapy for premenopausal patients
audio
Track 17 Use of an LHRH agonist and an aromatase inhibitor for premenopausal patients with high-risk disease

     
O'Regan Ruth O’Regan, MD
Director, Clinical and Translational Breast Cancer Research
Director, Hematology/Oncology Program
Associate Professor of Hematology/Oncology
Winship Cancer Institute
Emory University
Atlanta, Georgia

 
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Track 1 US Oncology trial of adjuvant docetaxel/cyclophosphamide (TC) versus AC
Track 2 Clinical trial of neoadjuvant docetaxel/capecitabine for triple-negative disease
Track 3 Study of nanoparticles to quantify key proteins in triple-negative disease
Track 4 Neoadjuvant HER2 trial of nab paclitaxel/trastuzumab arrow vinorelbine with trastuzumab
Track 5 Clinical utility of nab paclitaxel in breast cancer
Track 6 Neuropathy associated with nab versus standard-formulation paclitaxel

Track 7 Lack of premedication and shorter infusion time with nab paclitaxel
Track 8 Nab paclitaxel-containing combinations in the adjuvant and metastatic settings
Track 9 Identification of molecular targets in triple-negative disease
Track 10 Investigating targets for bevacizumab in the neoadjuvant setting
Track 11 Use of bevacizumab in clinical practice
audio
Track 12 Use of the Oncotype DX assay to predict pathologic complete response (pCR) to hormonal therapy
audio
Track 13 Italian study of neoadjuvant chemotherapy correlating pCR with Oncotype recurrence score
audio
Track 14 HER2 and relative resistance to hormonal therapy
audio
Track 15 Clinical trial strategies for triple-negative breast cancer
audio