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Publications discussed by Dr Elledge

Bundred NJ et al. Fulvestrant, an estrogen receptor downregulator, reduces cell turnover index more effectively than tamoxifen. Anticancer Res 2002;22(4):2317-9. Abstract

Carlson RW. Sequencing of endocrine therapies in breast cancer - integration of recent data. Breast Cancer Res Treat 2002;75 Suppl 1:S27-32; discussion S33-5. Abstract

Howell A et al. Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment. J Clin Oncol 2002;20(16):3396-403. Abstract

Howell A et al. Fulvestrant versus anastrozole for the treatment of advanced breast cancer: Survival analysis from a phase III trial. Proc ASCO 2003;Abstract 178.

Jones SE. A new estrogen receptor antagonist - an overview of available data. Breast Cancer Res Treat 2002;75 (Suppl 1):S19-21; discussion S33-5. Abstract

Mauriac L et al. Fulvestrant (Faslodex) versus anastrozole for the second-line treatment of advanced breast cancer in subgroups of postmenopausal women with visceral and non-visceral metastases: Combined results from two multicentre trials. Eur J Cancer 2003;39(9):1228-33. Abstract

Morris C, Wakeling A. Fulvestrant ('Faslodex') - a new treatment option for patients progressing on prior endocrine therapy. Endocr Relat Cancer 2002;9(4):267-76. Abstract

Osborne CK et al. Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: Results of a North American trial. J Clin Oncol 2002;20(16):3386-95. Abstract

Parker LM. Sequencing of hormonal therapy in postmenopausal women with metastatic breast cancer. Clin Ther 2002;24(Suppl C):C43-57.Abstract

Parker LM et al. Greater duration of response in patients receiving fulvestrant ('Faslodex') compared with those receiving anastrozole ('Arimidex'). Proc ASCO2002; Abstract 160.

Piccart M et al. Oestrogen receptor downregulation: An opportunity for extending the window of endocrine therapy in advanced breast cancer. Ann Oncol 2003;14(7):1017-25. Abstract

Pritchard KI. Endocrine therapy of advanced disease: Analysis and implications of the existing data. Clin Cancer Res 2003;9(1 Pt 2):460S-7S. Abstract

Robertson JF et al. Pharmacokinetics of a single dose of fulvestrant prolonged-release intramuscular injection in postmenopausal women awaiting surgery for primary breast cancer. Clin Ther 2003;25(5):1440-52. Abstract

Robertson JF, Harrison MP. Equivalent single-dose pharmacokinetics of two different dosing methods of prolonged-release fulvestrant ('Faslodex') in postmenopausal women with advanced breast cancer. Cancer Chemother Pharmacol2003. Abstract

Sommer A et al. Studies on the development of resistance to the pure antiestrogen Faslodex in three human breast cancer cell lines. J Steroid Biochem Mol Biol2003;85(1):33-47. Abstract

Steger GG et al. Fulvestrant beyond the second hormonal treatment line in metastatic breast cancer. Proc ASCO 2003;Abstract 78.

Vergote I et al. Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy. Breast Cancer Res Treat 2003;79(2):207-11. Abstract

Wardley AM. Fulvestrant: A review of its development, pre-clinical and clinical data. Int J Clin Pract 2002;56(4):305-9. Abstract

Watanabe T et al. Fulvestrant provides clinical benefit to postmenopausal women with metastatic breast cancer who have relapsed on prior antiestrogen therapy: A Japanese study. Proc ASCO 2003;Abstract 274.

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Howard A Burris III, MD
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Richard M Elledge, MD
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Rowan T Chlebowski, MD, PhD
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Vicente Valero, MD
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