Breast Cancer Update Patterns of Care 2005;2(3).
This publication reports the results of a Breast Cancer Patterns of Care survey,
completed in August and September of 2005 by 45 breast cancer clinical investigators
and 100 randomly selected United States-based medical oncologists,
designed to compare how these two groups of medical oncologists integrate
clinical research results into their practices. The adjuvant endocrine therapy
section of this publication is reviewed here.
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two to three years of tamoxifen therapy in postmenopausal women with primary breast
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Ingle JN et al. Analysis of duration of letrozole extended adjuvant therapy as measured
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breast cancer to anastrozole after 2 years’ adjuvant tamoxifen: Combined results of
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Jakesz R et al; ABCSG and the GABG. Benefits of switching postmenopausal women with
hormone-sensitive early breast cancer to anastrozole after 2 years adjuvant tamoxifen:
Combined results from 3,123 women enrolled in the ABCSG Trial 8 and the ARNO 95
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Jakesz R et al; Austrian Breast and Colorectal Cancer Study Group Trial 5. Randomized
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Kudachadkar R, O’Regan RM. Aromatase inhibitors as adjuvant therapy for postmenopausal
patients with early stage breast cancer. CA Cancer J Clin 2005;55(3):145-63. Abstract
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Thürlimann B et al. BIG1-98: Randomized double-blind phase III study to evaluate letrozole
(L) vs tamoxifen (T) as adjuvant endocrine therapy for postmenopausal women
with receptor-positive breast cancer. Presentation. ASCO 2005;Abstract 511.
Winer EP et al. American Society of Clinical Oncology technology assessment on the
use of aromatase inhibitors as adjuvant therapy for postmenopausal women with
hormone receptor-positive breast cancer: Status Report 2004. J Clin Oncol 2005;23(3):619-29. Abstract